一、个人简介
袁国瑞，西南大学植物保护学院昆虫学系教授，博士生导师。主要从事柑橘害虫（螨）的抗药性研究与昆虫学相关的教学工作。
先后主持国家自然科学基金、国家重点研发计划子课题、重庆市自然科学基金、博士后科学基金等10余项。在Pest Management Science, Pesticide Biochemistry and Physiology, BMC Biology, Archives of Insect Biochemistry and Physiology等重要国际学术刊物发表SCI论文20余篇，获授权专利1项，参编专著3部。昆虫学领域期刊审稿人、教育部学位与研究生教育发展中心教育评估监测专家库成员、重庆市科技特派员、第四批全国高校黄大年式教师团队成员，承担国家一流本科课程《农业昆虫学》《生态学》及研究生课程《昆虫生理生化》的教学工作。
二、教育和工作经历
2004.9 - 2011.6 南京农业大学 农业昆虫与害虫防治 农学博士（硕博连读）
2009.3 - 2010.8 澳大利亚CSIRO昆虫研究所 联合培养博士
2000.9 - 2004.6 河南农业大学 植物保护 农学学士
2013.3 - 2017.8 西南大学植物保护博士后流动站 在职博后
2011.7至今 西南大学植物保护学院从事教学和科研工作
三、研究方向
1.柑橘害虫（实蝇/螨）田间抗药性演化
2.柑橘害虫抗药性机制及其调控的分子机制
3.新型杀虫剂抗性风险评估
四、主要项目
1. 国家自然科学基金面上项目：柑桔全爪螨GATAe调控PcCarE1表达介导多药抗性的分子机制，32673275，2027-2030。
2. 国家自然科学基金面上项目：CncC调控Cyp392A24过表达介导柑桔全爪螨对阿维菌素抗性的分子机制，31972272，2020-2023。
3. 国家重点研发计划项目子课题：果树重要虫害抗药性治理技术研发及示范应用，2022YFD1400905-5，2022-2025。
4. 国家重点研发计划项目子课题：西南柑橘化学农药减施技术研究与示范，2017YFD0202006-03，2017-2020。
5. 重庆市自然科学基金面上项目：柑桔全爪螨UGT202A7过表达介导阿维菌素抗性的分子调控机制，CSTB2024NSCQ-MSX0696，2024-2027。
6. 重庆市基础科学与前沿技术研究项目：桔小实蝇对马拉硫磷抗性相关microRNA的鉴定与功能分析，cstc2018jcyjAX0008，2018-2021。
7. 重庆市基础科学与前沿技术研究项目：基于RNAi的桔小实蝇鱼尼丁受体基因的功能研究，cstc2017jcyjA0587，2017-2020。
五、科研论文
1. Li Ke, Zhang Chunyu, Ren Yiting, Liu Xunyan, Pan Deng, Dou Wei, Wang Jinjun, Yuan Guorui*. 2025. Risk assessment of broflanilide resistance in Panonychus citri (McGregor): Cross-resistance, inheritance and relative fitness. Pestic. Biochem. Physiol. 208: 106256. (https://doi.org/10.1016/j.pestbp.2024.106256).
2. Li Ke, Ren Yiting, Liu Xunyan, Pan Deng, Dou Wei, Wang Jinjun, Yuan Guorui*. 2024. Sublethal and transgenerational effects of broflanilide on the citrus red mite, Panonychus citri. Pest Manag. Sci. 80(10): 5412-5420. (https://doi.org/10.1002/ps.8270).
3. Ren Yiting, Dou Wei, Wang Jinjun, Yuan Guorui*. 2024. Lethal and sublethal effects of fluralaner on the citrus red mite, Panonychus citri (McGregor). Pest Manag. Sci. 80(7): 3308-3316. (https://doi.org/10.1002/ps.8034).
4. Liu Xunyan, Li Ke, Pan Deng, Dou Wei, Yuan Guorui*, Wang Jinjun*. 2024. Cross-resistance, inheritance and biochemical mechanism of abamectin resistance in a field-derived strain of the citrus red mite, Panonychus citri (Acari: Tetranychidae). Pest Manag. Sci. 80(3): 1258-1265. (https://doi.org/10.1002/ps.7855).
5. Zhang Shuxia, Chen Mengling, Meng Liwei, Dou Wei, Wang Jinjun, Yuan Guorui*. 2023. Functional analysis of an overexpressed glutathione S-transferase BdGSTd5 involved in malathion and malaoxon detoxification in Bactrocera dorsalis. Pestic. Biochem. Physiol. 194: 105498. (https://doi.org/10.1016/j.pestbp.2023.105498).
6. Li Zhenyu, Chen Mengling, Bai Wenjie, Zhang Shuxia, Meng Liwei, Dou Wei, Wang Jinjun, Yuan Guorui*. 2023. Identification, expression profiles and involvement in insecticides tolerance and detoxification of carboxylesterase genes in Bactrocera dorsalis. Pestic. Biochem. Physiol. 193: 105443. (https://doi.org/10.1016/j.pestbp.2023.105443).
7. Chen Mengling, Zhang Shuxia, Guo Pengyu, Qin Qingshi, Meng Liwei, Yuan Guorui*, Wang Jinjun*. 2023. Identification and characterization of UDP-glycosyltransferase genes and the potential role in response to insecticides exposure in Bactrocera dorsalis. Pest Manag. Sci. 79(2): 666-667. (https://doi.org/10.1002/ps.7234).
8. Meng Liwei#, Yuan Guorui#, Chen Mengling, Zheng Lisha, Dou Wei, Peng Yu, Bai Wenjie, Li Zhenyu, Vontas John, Wang Jinjun*. 2023. Cuticular competing endogenous RNAs regulate insecticide penetration and resistance in a major agricultural pest. BMC Biology. 21: 287. (https://doi.org/10.1186/s12915-023-01694-z).
9. Yuan Guorui, Chen Mengling Chen, Peng Menglan, Lei Wei, Meng Liwei, Dou Wei, Wang Jinjun*. 2022. Knockdown of a nicotinic acetylcholine receptor subunit gene Bdorβ1 decreases susceptibility to oxa-bridged trans-instead of cis-nitromethylene neonicotinoid insecticides in Bactrocera dorsalis. J. Agric. Food Chem. 70(42): 13554-13562. (https://doi.org/10.1021/acs.jafc.2c04709).
10. Meng Liwei#, Yuan Guorui#, Chen Mengling, Dou Wei, Jing Tianxing, Zheng Lisha, Peng Menglan, Bai Wenjie, Wang Jinjun*. 2021. Genome-wide identification of long non-coding RNAs (lncRNAs) associated with malathion resistance in Bactrocera dorsalis. Pest Manag. Sci. 77(5): 2292-2301. (https://doi.org/10.1002/ps.6256).
11. Meng Liwei, Peng Menglan, Chen Mengling, Yuan Guorui, Zheng Lisha, Bai Wenjie, Smagghe Guy*, Wang Jinjun*. 2020. A glutathione S-transferase (BdGSTd9) participates in malathion resistance via directly depleting malathion and its toxic oxide malaoxon in Bactrocera dorsalis (Hendel). Pest Manag. Sci. 76(8): 2557-2568. (https://doi.org/10.1002/ps.5810).
12. Meng Liwei, Yuan Guorui, Lu Xueping, Jing Tianxing, Zheng Lisha, Yong Hanxiao, Wang Jinjun*. 2019. Two delta class glutathione S-transferases involved in the detoxification of malathion in Bactrocera dorsalis (Hendel). Pest Manag. Sci. 75(6):1527-1538. (https://doi.org/10.1002/ps.5318).
13. Yuan Guorui, Wang Keyi, Mou Xing, Luo Ruoyu, Dou Wei, Wang Jinjun*. 2017. Molecular cloning, mRNA expression and alternative splicing of a ryanodine receptor gene from the citrus whitefly, Dialeurodes citri (Ashmead). Pestic. Biochem. Physiol. 142: 59-66. (https://doi.org/10.1016/j.pestbp.2017.01.005).
14. Mou Xing, Yuan Guorui, Jiang Hongbo, Liu Zhao, Wang Jinjun*. 2017. Functional characterization of two acetylcholinesterase genes in the brown citrus aphid, Aphis (Toxoptera) citricidus (Kirkaldy), using heterologous expression and RNA interference. Pestic. Biochem. Physiol. 138: 76-83. (https://doi.org/10.1016/j.pestbp.2017.03.004).
15. 袁国瑞, 杨文佳, 许抗抗, 王进军*. 2016. 橘小实蝇nAChR α9亚基基因的鉴定及其时空表达. 昆虫学报, 59: 1189-1198. (DOI：10.16380/j.kcxb.2016.11.006)
16. Yuan Guorui, Li Yongqiang, Farnsworth Claire, Coppin Chris, Devonshire AL, Scott Collin, Russell Robyn, Wu Yidong, Oakeshott John*. 2015. Isomer-specific comparisons of the hydrolysis of synthetic pyrethroids and their fluorogenic analogues by esterases from the cotton bollworm Helicoverpa armigera. Pestic. Biochem. Physiol. 121: 102-106. (https://doi.org/10.1016/j.pestbp.2014.12.010).
17. Wang Luoluo, Huang Yong, Lu Xueping, Jiang Xuanzhao, Smagghe Guy, Feng Zijiao, Yuan Guorui, Wei Dong and Wang Jinjun*. 2015. Overexpression of two-α-esterase genzhi, Yang Wenjia, Jiang Xuanzhao, Dou Wei, Wang Jinjun*. 2014. Molecular characteristics, mRNA expression, and alternative splicing of a ryanodine receptor gene in the oriental fruit fly, Bactrocera dorsalis (Hendel). PLOS ONE. 9(4): e95199. (https://doi.org/10.1371/journal.pone.0095199).
18. 李永强, 袁国瑞, 张兴*. 2012. 两个棉铃虫酯酶基因（001f和001g）在杆状病毒表达载体系统（BEVS）中的表达及酶活分析, 农业生物技术学报, 20(1): 70-78. (DOI: 10.3969/j.issn.1674-7968.2012.01.010）
19. 李永强, 袁国瑞, 安凤秋, 苏立德, 冯俊涛, 张兴*. 2012. 基于定量PCR技术的AcNPV-CarE病毒液滴度测定及酯酶表达条件优化, 西南大学学报（自然科学版）, 34(10): 41-47. (DOI:10.13718/j.cnki.xdzk.2012.10.020).
20. Wu Shuwen, Yang Yihua, Yuan Guorui, Campbell Peter, Teese Mark, Russell Robyn, Oakeshott John, Wu Yidong*. 2011. Overexpressed esterases in a fenvalerate resistant strain of the cotton bollworm, Helicoverpa armigera. Insect Biochem. Molec. Biol. 41(1): 14-21. (https://doi.org/10.1016/j.ibmb.2010.09.007)
21. Yuan Guorui, Gao Weiyue, Yang Yihua, and Wu Yidong*. 2010. Molecular cloning, genomic structure and genetic mapping of two Rdl-orthologous genes of GABA receptors in the diamondback moth, Plutella xylostella. Arch. Insect Biochem. Physiol.74(2): 81-90. (https://doi.org/10.1002/arch.20361)
22. Farnsworth Claire, Teese Mark, Yuan Guorui, Li Yongqiang, Scott Collin, Zhang Xing, Wu Yidong, Russell Robyn, Oakeshott John*. 2010. Esterase-based metabolic resistance to insecticides in heliothine and spodopteran pests. J. Pestic Sci. 35(3): 275-289. (https://doi.org/10.1584/jpestics.R10-13)
六、联系方式
重庆市北碚区天生路2号，西南大学植物保护学院，400715。
E-mail: ygr@swu.edu.cn
